Good ingredients are already abundant. Countless skincare products talk about better ingredients, higher concentrations, stronger efficacy. But we asked a different question: Why doesn't skin change easily, even with good ingredients? The answer we found wasn't ingredients — it was Reach. Skin change isn't created by ingredients. It begins the moment they truly reach.

Precision Delivery

Meltryx opens microscopic channels in the stratum corneum, delivering actives as it dissolves in moisture. Redefined not as injection but as pathway design.

Verified Reach

We replace instant results with measured data - 520% higher absorption, 600µm penetration - building trust through verified numbers, not immediacy.

Micro Precision

We connect skin science directly to our core statement: Micro Precision, Beneath the Skin. Not abstract innovation, but concrete language that starts at an invisible scale.

No matter how powerful an ingredient is, it won't work if it never reaches the skin. Meltryx® creates the pathway in the stratum corneum, and NAD+ is delivered deep into the skin through that pathway. Neither works alone. Change begins only when pathway and ingredient work together.

Meltryx is a star-shaped particle engineered with HA and hydrolyzed collagen. Inspired by the micro-channel principle of microneedling, it creates gentle micro-stimulation and micro-channels in the stratum corneum by rolling instead of needles, then dissolves within 30 seconds on contact with moisture. Actives travel along the channels. No insertion, zero residue.

STEP 02 is engineered to work through the pathway MELTRYX® creates. At its heart: NMN, the building block of NAD+, together with NAD+ itself. NAD+ is the coenzyme behind cellular energy and repair, and it declines with age. A peptide complex and madecassoside support skin condition; ectoin and panthenol support the barrier. Create the conditions for skin to change on its own. MELTRYX® opens the pathway. NMN creates the starting point.

The two actives in Step 02

NiacinamideNMNNAD+

NAMPT
slowest step

NMNAT
one step

01. NMN for NAD+, as the lead active

NAD+ is essential for skin cell energy and repair, but its levels decline with age. As the final building block, NMN bypasses the slowest step and converts into NAD+ in a single enzymatic reaction.

02. Rolling micro-stimulation,
into the deeper stratum corneum

Inspired by microneedling, needle-free rolling creates gentle micro-pathways in the stratum corneum, letting water-loving NMN, which cannot cross this layer on its own, travel deeper into the skin.

03. Firmness and vitality for tired skin

By feeding the NAD+ pathway, Step 02 cares for skin that has lost energy and resilience. A peptide complex supports firmness, while ectoin, panthenol and madecassoside support the barrier and soothe.

• ➀

  24h absorption vs. control

  520%

  5.2x the control group under peak-strength conditions (5M-10R). Franz diffusion cell. Standard apparatus for measuring the amount of a substance passing through skin.

  control100%3h 10% · 5h 18%

  1M-5R164%3h 16% · 5h 28%

  5M-5R332%3h 31% · 5h 57%

  5M-10R520%3h 50% · 5h 88%
• ➁

  Skin Penetration Depth

  600µm

  Fluorescent tracer (calcein) cross-section analysis. Reaches the dermal papillary layer.

• ➂

  Full Dissolution Time

  30sec

  Fully dissolves without residue upon contact with an aqueous environment. No rinsing required.

• ➃

  Compressive Fracture Strength

  9.6N

  ±2.3N. Sufficient mechanical strength to maintain structure while rolling.

• ➄

  Biocompatible Material

  HA+HCol

  Hyaluronic acid + hydrolyzed collagen. No foreign-body reaction.

Co-developed by GN Biosolution and QuadMedicine. Produced at a dedicated Meltryx AI robotics plant completed in July 2026, with production now underway. QuadMedicine is a Korean biotech company specializing in transdermal delivery technology. Its innovation has been recognized through citations in international SCIE-indexed journals (impact factor 9.0+) for delivery performance reaching deep into the skin.